2025 On-Demand: Basic Science Focus Forum
- Basic Science Focus Forum Symposium I: Orthobiologics: In Collaboration with International Section of Fracture Repair (ISFR)
- Basic Science Focus Forum Podium Session I: Musculoskeletal Healing
- Moderator(s) Michael Hast, PhD Brian (Vu) Le, MD (he/him/his) Presentations: 8:35 AM - 8:41 AM MSTHarnessing the Power of Nature: mRNA-Activated Biomimetic Hematoma Scaffold for Volumetric Muscle Loss Regeneration Presenting Author / Corresponding Author: Vaida Glatt, PhD (she/her/hers) – UT Health San Antonio Co-Author: Joshua Choe, MD – University of Wisconsin Co-Author: William Murphy, PhD – University of Wisconsin 8:41 AM - 8:47 AM MSTCo-Delivery of Mesenchymal Stem Cells and Disordered Peptides Attenuates the Inflammatory Response and Improves Fracture Healing in Polytrauma Presenting Author / Corresponding Author: Augustine M. Saiz, Jr., MD (he/him/his) – UC Davis Group Author: Group Author Mechanistic Polytrauma Working Group 8:47 AM - 8:53 AM MSTInjury-Associated Anemia Attenuates Fracture Healing Presenting Author / Corresponding Author: Victoria Duke, BS – OHSU Co-Author: Cynthia Alcazar, PhD – OHSU Co-Author: Natasha S. McKibben, MD – Oregon Health & Science University Co-Author: Zachary M. Working, MD – Oregon Health & Science University Co-Author: Nick J. Willett, PhD – University of Oregon Co-Author: Karina Nakayama, PhD (she/her/hers) – Oregon Health & Science University 8:53 AM - 8:59 AM MSTThe Role of Human Hematoma and Soft Callus in Fracture Healing Presenting Author / Corresponding Author: Ting Zheng, PhD – Hospital for special surgery Co-Author: Schimizzi Gregory, MD, PhD – Hospital for Special Surgery Co-Author: Robert E. Bilodeau, BS – University of Pittsburgh Co-Author: Ruge Chen, BS – Hospital for Special Surgery Co-Author: Kathryn A. Barth, MD – Hospital for Special Surgery Co-Author: Heather Haeberle, MD – UTHealth Houston Co-Author: Alona Katzir, MD – Hospital for Special Surgery Co-Author: Klinger E. Craig, MPH – Hospital for Special Surgery Co-Author: William M. Ricci, MD – Hospital for Special Surgery Co-Author: Baohong Zhao, PhD – hospital for Special Surgery 9:09 AM - 9:15 AM MSTInhibition of CAMKK2 Signaling and ROS Mitigates PTOA After Acute Cartilage Injury Presenting Author / Corresponding Author: Julian E. Dilley, MD – Indiana University School of Medicine Co-Author: Aaron Nanavaty, BA – Indiana University School of Medicine Co-Author: Keegan Riggs, BS – Indiana University School of Medicine Co-Author: Nyssa Qiao, BS – Indiana University School of Medicine Co-Author: Abhijit Seetharam, MD – Indiana University School of Medicine Co-Author: Hessam Noori-Dokht, PhD – Purdue University Co-Author: Diane Wagner, PhD – Purdue University Co-Author: Roman Natoli, MD, PhD – Indiana University School of Medicine Co-Author: Todd O. McKinley, MD – Indiana University School of Medicine Co-Author: Uma Sankar, PhD – Indiana University School of Medicine 9:15 AM - 9:21 AM MSTIGF1-Integrated Muscle Void Fillers for Interim Support in Volumetric Muscle Loss Co-Author: Andrew Clark, PhD – Henry M Jackson Foundation Co-Author: Claudia Hernandez – C2 Alaska Co-Author: Chun-Hui Su, PhD – C2 Alaska Co-Author: Roman Natoli, MD, PhD – Indiana University School of Medicine Co-Author: Todd O. McKinley, MD – Indiana University School of Medicine Co-Author: Christopher Dearth, PhD – Defense Health Agency Presenting Author / Corresponding Author: Stephen Goldman, PhD – Defense Health Agency 9:21 AM - 9:27 AM MSTCollagen X Longitudinal Fracture Biomarker Expression Demonstrates Similar Endochondral Activity in Intra and Extra-articular Fractures Co-Author: Caellagh D. Catley, MD – OHSU Co-Author: Catherine ET Hutchison, MD – Oregon Health & Science University Co-Author: Natasha S. McKibben, MD – Oregon Health & Science University Co-Author: Talia Trapalis, BS – Oregon Health & Science University Co-Author: Colby Curtis, BS – Oregon Health & Science University Co-Author: Dane Brodke, MD, MPH – UCLA Co-Author: Graham Dekeyser, MD – University of Utah Co-Author: Darin M. Friess, MD – Oregon Health & Science University Co-Author: Chelsea S. Bahney, PhD (she/her/hers) – UCSF Presenting Author / Corresponding Author: Zachary M. Working, MD – Oregon Health & Science University
- Basic Science Focus Forum Symposium II: AI: It’s in Your Phone, Why Not Your Practice?
- Basic Science Focus Forum Podium Session II: Polytrauma
- Moderator(s) Donald Anderson, PhD The University of Iowa Shuyang Han, PhD Presentations: 10:50 AM - 10:56 AM MSTRaman Spectroscopy: Investigating the Predictive Value for Fracture Presenting Author / Corresponding Author: Andrew J. Rodenhouse, MD – University of Rochester Medical Center Co-Author: Kyle Jerreld, BS – University of Rochester Medical Center Co-Author: Anthony Yosick, BS – University of Rochester Medical Center Co-Author: Sashank Lekkala, MS – University of Rochester Medical Center Co-Author: Andrew Berger, PhD – University of Rochester Co-Author: Hani Awad, PhD – University of Rochester Medical Center Co-Author: Constantinos Ketonis, MD, PhD – University of Rochester Medical Center 10:56 AM - 11:02 AM MSTSystemic longitudinal Immune Profiling to Noninvasively Predict Fracture Nonunion Presenting Author / Corresponding Author: Kelly Leguineche, MS – University of Oregon Co-Author: Jena Robinson, BS, CCRP – Indiana University Health Co-Author: Lauren Hill, BS, CCRC – Indiana University Health Co-Author: Danielle Olson, BS – NYU Langone Orthopedic Hospital Co-Author: Raj Karia, MPH – NYU Langone Orthopedic Hospital Co-Author: Samantha Nino, MD Co-Author: Auveen Hajarizadeh, BS – University of Oregon Co-Author: Kimberly Jones, PhD – University of Oregon Co-Author: Roman Natoli, MD, PhD – Indiana University School of Medicine Co-Author: Philipp Leucht, MD – NYU Langone Orthopedics Co-Author: Todd O. McKinley, MD – Indiana University School of Medicine Co-Author: Robert Guldberg, PhD – University of Oregon 11:02 AM - 11:08 AM MSTDistinct Immunologic Mediators Are Associated with Venous Thromboembolism in Polytrauma Patients Presenting Author / Corresponding Author: Prism Schneider, MD, PhD (she/her/hers) – University of Calgary Co-Author: Peter Quinn, BSc – St. Johns College, Annapolis Co-Author: Renan Castillo, MD – John Hopkins Bloomberg School of Public Health Co-Author: Greg E. Gaski, MD – Inova Fairfax Medical Campus Co-Author: Katherine Frey, PhD (she/her/hers) – Johns Hopkins University Bloomberg School of Public Health Co-Author: Seth A. Schobel, PhD – Uniformed Services University Co-Author: Felipe A. Lisboa, MD – Uniformed Services University Co-Author: Henry Robertson, PhD – Uniformed Services University Co-Author: Timothy R. Billiar, MD – Univ of Pittsburgh Medical Center Co-Author: Eric Elster, MD – Uniformed Services University Co-Author: Laurence b. kempton, MD – Atrium Health Carolinas Medical Center Co-Author: Reza Firoozabadi, MD, MA – University of Washington, Harborview Medical Center Co-Author: Joshua L. Gary, MD – University of Southern California Co-Author: Stephen J. Warner, MD, PhD – University of Texas at Houston, McGovern Medical School Co-Author: William T. Obremskey, MD, MPH, FIOTA (he/him/his) – Vanderbilt University Medical Center Co-Author: Robert O’Toole, MD – University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center Co-Author: Arun Aneja, MD, PhD (he/him/his) – Massachusetts general Brigham Co-Author: Eric Gann, PhD – Uniformed Services University Co-Author: Simon Tallowin, BMBS, MSc – Uniformed Services University, Royal Centre for Defence Medicine, UK Co-Author: Todd O. McKinley, MD – Indiana University School of Medicine Group Author: Group Author Major Extremity Trauma Research Consortium (METRC) 11:18 AM - 11:24 AM MSTThe Effect of Retrograde Nail Tip Location on Proximal Femur Fracture: A Finite Element Study with Validation Presenting Author / Corresponding Author: Gregory R. Roytman, DC, MS – Yale School of Medicine Co-Author: Sarah E. Rizzo, MD – University of Rochester Co-Author: Jay Moran, MD – Yale School of Medicine Co-Author: Brad J. Yoo, MD – Yale School of Medicine Co-Author: Steven M. Tommasini, PhD – Yale School of Medicine Co-Author: Daniel H. Wiznia, MD – Yale School of Medicine Co-Author: Brianna R. Fram, MD (she/her/hers) – University of Chicago School of Medicine 11:24 AM - 11:30 AM MSTRisk of Nonunion and Revision Surgery with Early Bisphosphonate Use in Proximal Femoral Fractures Co-Author: Mehul Mittal, BS – Washington University Orthopedics Co-Author: Aruni Areti, BS – Washington University Orthopedics Co-Author: Aaron Singh, MD – UTHSCSA Presenting Author / Corresponding Author: Daniel E. Pereira, MD – Washington University Orthopedics Co-Author: Pooya Hosseinzadeh, MD – Washington University Orthopedics Co-Author: Mahshid Mohseni, MD – Washington University Orthopedics 11:30 AM - 11:36 AM MSTIncreased Platelet Activity Follows Hip Fracture Surgery Compared to Elective Total Hip Arthroplasty Presenting Author / Corresponding Author: Daniyya Chaudhry, PhD Candidate – University of Calgary Co-Author: Golpira Elmi Assadzadeh, PhD – University of Calgary Co-Author: Souvik Maiti, BSc – University of Calgary Co-Author: Jessica Duong, PhD – University of Calgary Co-Author: Robert Korley, MD – University of Calgary Co-Author: Paul James Duffy, MD – University of Calgary Co-Author: Prism Schneider, MD, PhD (she/her/hers) – University of Calgary
- Basic Science Focus Forum Podium Session III: New Techniques in Patient Care
- Moderator(s) Zachary Working, MD Dillon O'Neill, MD (he/him/his) Presentations: 12:45 PM - 12:51 PM MSTImplantable Strain Sensors Revealed Higher Strain Thresholds for Robust Fracture Healing Presenting Author / Corresponding Author: Kylie E. Williams, PhD – Penderia Technologies Inc. Co-Author: Farhan Muhib, BSc – University of Utah Co-Author: Jeffrey A. Weiss, PhD – University of Utah Co-Author: Robert Guldberg, PhD – University of Oregon Co-Author: Ghee Ong, PhD – Penderia Technologies Inc. 12:51 PM - 12:57 PM MSTInfill Architecture Influences Bone Growth in 3D Printed PCL Scaffolds Co-Author: Hisham Omar, MS – University of Delaware Co-Author: Paulina Bargallo Gonzalez Lugo, BS – University of Pennsylvania Co-Author: Rachel Bonfini, BS – University of Delaware Co-Author: Matthew Fainor, BS – University of Pennsylvania Co-Author: Sarah Gullbrand, PhD – University of Pennsylvania Presenting Author / Corresponding Author: Michael W. Hast, PhD – University of Delaware 12:57 PM - 1:03 PM MSTRight Femur Fractures: Establishing a Timeline for Returning to Drive Using a Braking Simulator Device Co-Author: Daniel S. Horwitz, MD – Geisinger Medical Center Co-Author: Claire E. Hayes, BS – Biomedical Engineering Dept., Bucknell University Co-Author: Daniel Hayes, BS – Geisinger Health System Presenting Author / Corresponding Author: Ahmed Nageeb Mahmoud, MD, MSc, PhD (he/him/his) – Geisinger Medical Center; Faculty of Medicine, Ain Shams University Faculty of Medicine Co-Author: Zane David Patterson, BS – Biomedical Engineering Dept., Bucknell University Co-Author: Joseph Patrick Carrey, BS – Mechanical Engineering Dept., Bucknell University Co-Author: Eric A. Kennedy, PhD – Biomedical Engineering Dept., Bucknell University 1:13 PM - 1:19 PM MSTFixation of B3 Sacral Fractures Utilizing a Novel Compressive Bolt – A Biomechanical Comparison Co-Author: Devin Froerer, MD – University of Utah Co-Author: Sebastion Jensen – University of Utah Co-Author: Colin Gregersen, MS – University of Utah Presenting Author / Corresponding Author: Justin M. Haller, MD – University of Utah 1:19 PM - 1:25 PM MSTDynamic Interfragmentary Compression Through a Tibial Intramedullary Nail Compared to Backslapping Alone: A Biomechanical Analysis Presenting Author / Corresponding Author: Brittany Haws, MD – Emory University Co-Author: Daniel Thompson, ME, BS – Emory University Co-Author: Jonathan Yawman, MD – Emory University Co-Author: Jana M. Davis, MD (she/her/hers) – Division of Orthopaedic Trauma Penn State Hershey Medical Center Co-Author: Nina Suh, MD – Emory University Co-Author: James A. Blair, MD (he/him/his) – Emory University School of Medicine at Grady Memorial Hospital 1:25 PM - 1:31 PM MSTNerve to Artery Coaptation for Neuroma Prevention: A Pilot Study Co-Author: Tyler D. Ragsdale, MD – St. Louis University Presenting Author / Corresponding Author: Benjamin Nwadike, MD – St. Louis University Co-Author: J. Tracy Watson, MD – St. Louis University School of Medicine
- Basic Science Focus Forum Symposium III: Fracture Related Infection: In Collaboration with Musculoskeletal Infection Society (MSIS)
- Basic Science Focus Forum Podium Session IV: Infection
- Moderator(s) Justin Haller, MD John Wixted, MD Presentations: 2:55 PM - 3:01 PM MSTHalicin Increases Rifampicin Potency and Prevents Resistance Against S. aureus Biofilms Presenting Author / Corresponding Author: Allison Wintring, MD – Indiana University Co-Author: Joash Suryavanshi, MD – Indiana University Co-Author: Akira Morita, MD, PhD – Yokohama City University Co-Author: Roman Natoli, MD, PhD – Indiana University School of Medicine Co-Author: Edward Greenfield, PhD – Indiana University 3:01 PM - 3:07 PM MSTTemporal Effects on Intraoperative Bacterial Contamination of Surgical Gloves in Non-infection Orthopaedic Trauma Cases Presenting Author / Corresponding Author: Arya Amirhekmat, BS – UC Irvine Co-Author: Julie Shimabukuro, BS – UC Irvine Co-Author: Cassiana Bittencourt, MD – UC Irvine Co-Author: James R. Learned, MD, BA (he/him/his) – UCI Health Co-Author: John A. Scolaro, MD, MA (he/him/his) – University of California, Irvine Co-Author: Philip Lim, MD – UC Irvine 3:07 PM - 3:13 PM MSTPlasma Metabolomics Discriminates Patients with Fracture-Related Infection from Uninfected Controls Presenting Author: Priyanka Ghosh, MD – Department of Orthopaedic Surgery, Indiana University School of Medicine Co-Author: Lauren Hill, BS, CCRC – Indiana University Health Co-Author: Makenzie Barger, MS – Department of Orthopaedic Surgery, Indiana University School of Medicine Co-Author: Sarah Malek, DVM, PhD – Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University Corresponding Author: Roman Natoli, MD, PhD – Indiana University School of Medicine 3:13 PM - 3:19 PM MSTImpact of Preoperative Antibiotic Administration on Culture Positivity in Musculoskeletal Infections: A Preclinical Investigation Presenting Author: Lauren Luther, MD – Vanderbilt University Medical Center Co-Author: Brittney D. Gimza, PhD – Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center Co-Author: Kara Eichelberger, PhD – Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center Co-Author: Stephanie Moore-Lotridge, PhD – Department of Orthopaedic Surgery, Vanderbilt University Medical Center Co-Author: Michael A. Quacinella, DO – Scripps Mercy Hospital Co-Author: Jonathan G. Schoenecker, MD, PhD – Department of Orthopaedic Surgery, Vanderbilt University Medical Center Co-Author: James E. Cassat, MD, PhD – Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center Corresponding Author: William T. Obremskey, MD, MPH, FIOTA (he/him/his) – Vanderbilt University Medical Center 3:29 PM - 3:35 PM MSTBactericidal Efficacy of Bacterial Load Reduction Techniques Against Biofilm Presenting Author: Peter Mittwede, MD, PhD – The University of Mississippi Medical Center Corresponding Author: Chelsey E. Smith, MD – The University of Mississippi Medical Center Co-Author: Patrick F. Bergin, MD – University of Mississippi Medical Center Co-Author: Dillon C. O'Neill, MD (he/him/his) – Indiana University School of Medicine 3:35 PM - 3:41 PM MSTDeficient Epithelial and Adaptive Immunologic Mediators Predict Organ Dysfunction in Patients Treated with Early Total Care (ETC) Co-Author: Greg E. Gaski, MD – Inova Fairfax Medical Campus Presenting Author: Prism Schneider, MD, PhD (she/her/hers) – University of Calgary Co-Author: Katherine Frey, PhD (she/her/hers) – Johns Hopkins University Bloomberg School of Public Health Co-Author: Timothy R. Billiar, MD – Univ of Pittsburgh Medical Center Co-Author: Renan Castillo, MD – John Hopkins Bloomberg School of Public Health Co-Author: Robert V. O'Toole, MD – University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center Co-Author: Reza Firoozabadi, MD, MA – University of Washington, Harborview Medical Center Co-Author: William T. Obremskey, MD, MPH, FIOTA (he/him/his) – Vanderbilt University Medical Center Co-Author: Laurence b. kempton, MD – Atrium Health Carolinas Medical Center Co-Author: Stephen J. Warner, MD, PhD – University of Texas at Houston, McGovern Medical School Co-Author: Arun Aneja, MD, PhD (he/him/his) – Massachusetts general Brigham Corresponding Author: Todd O. McKinley, MD – Indiana University School of Medicine Group Author: METRC Group 3:41 PM - 3:47 PM MSTMetabolomics after Polytrauma – A Biobank Analysis of 97 Patients Over the Time Course of 10 Days Corresponding Author: Felix Klingebiel, MD – University Hospital Zürich / Traumatology Department Presenting Author: Christian T. Hübner, MD – University Hospital Zürich / Traumatology Department Co-Author: Yannik Kalbas, MD – University Hospital Zürich / Traumatology Department Co-Author: Sascha Halvachizadeh, MD – University Hospital Zürich Co-Author: Michel PJ Teuben, MD, PhD (he/him/his) – University Hospital Zürich Co-Author: Bergita Ganse, MD – Werner Siemens Foundation Endowed Chair for Innovative Implant Development Co-Author: Paolo Cinelli, PD, PhD – University Hospital Zurich Co-Author: Hans-Christoph Pape, MD, FIOTA (he/him/his) – Universitätsspital Zürich Co-Author: Roman Pfeifer, MD (he/him/his) – University Hospital Zürich / Traumatology Department
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Basic Science Focus Forum Podium Session I: Musculoskeletal Healing
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Open to view video.
Basic Science Focus Forum Podium Session III: New Techniques in Patient Care
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Open to view video.
Basic Science Focus Forum Symposium I: Orthobiologics: In Collaboration with International Section of Fracture Repair (ISFR)
Open to view video.
Open to view video.
Moderator(s)
Michael Hast, PhD
Brian (Vu) Le, MD (he/him/his)
Presentations:
7:35 AM - 7:45 AM MSTInducing Better Masquelet Membranes with Orthobiologics
Presenter: J. Tracy Watson, MD – St. Louis University School of Medicine
7:45 AM - 7:55 AM MSTHydroxyapatite Coating Mitigates Degradation of Additively Manufactured Magnesium Scaffolds
Presenter: Lauren Priddy, PhD
7:55 AM - 8:05 AM MSTNature-Inspired Healing: Clinical Potential of Biomimetic Hematoma Scaffold (tentative title)
Presenter: Vaida Glatt, PhD (she/her/hers) – UT Health San Antonio
8:05 AM - 8:15 AM MSTStrategies to Enhance Musculoskeletal Recovery After Traumatic Injury
Presenter: Katherine R. Hixon, PhD – Dartmouth College
Basic Science Focus Forum Symposium II: AI: It’s in Your Phone, Why Not Your Practice?
Open to view video.
Open to view video.
Moderator(s)
DA
Donald Anderson, PhD
The University of Iowa
Financial Disclosures: Iowa Simulation Solutions: Other Business Ownership
SH
Shuyang Han, PhD
This individual reported nothing to disclose.
Krystin Hidden, MD photo
Krystin Hidden, MD
Assistant Professor
Orthopedic Surgery
Mayo Clinic
Mayo Clinic, Minnesota, United States
Financial Disclosures: Johnson and Johnson, Stryker: Consultant
Presentations:
9:50 AM - 10:00 AM MSTOTA AI Task Force: Accomplishments, Insights & Future of AI Within and the OTA
Presenter: Meir T. Marmor, MD MIDS (he/him/his) – University of California San Francisco
10:00 AM - 10:10 AM MSTThe Use of AI in Fall Prevention for the Elderly
Presenter: Thurmon Lockhart, PhD (he/him/his) – Arizona State University
10:10 AM - 10:20 AM MSTSynergies Between Traditional Computational Modeling and Machine Learning – Towards in Silico Clinical Trials
Presenter: Steven P. Mell, PhD – Rush University
10:20 AM - 10:30 AM MSTApplying AI to Study Intertrochanteric Fracture Fixation
Presenter: Linjun Yang, PhD
Basic Science Focus Forum Symposium III: Fracture Related Infection: In Collaboration with Musculoskeletal Infection Society (MSIS)
Open to view video.
Open to view video.
Moderator(s)
Justin Haller, MD
John Wixted, MD (he/him/his)
Presentations:
1:55 PM - 2:05 PM MSTFluorescence-Guided Debridement
Presenter: Leah Gitajn, MD, MS – Dartmouth-Hitchcock Medical Center
2:05 PM - 2:15 PM MSTInfection Biomarkers and Next Generation Sequencing - Are They Infected? What Are the Pathogens
Presenter: Roman Natoli, MD, PhD – Indiana University School of Medicine
2:15 PM - 2:25 PM MSTAntibiotic Management of Fracture Related Infections
Presenter: Laura Certain, MD, PhD (she/her/hers) – University of Utah
2:25 PM - 2:35 PM MSTOperative Techniques for Infection Outside My Wheelhouse
Presenter: Richard S. Yoon, MD, FIOTA, FAOA – OrthoComplex
